This Pioneer Woman Chicken Biscuit Casserole is a creamy and comforting recipe, which is made with refrigerated biscuits and shredded cheddar cheese. It’s the ultimate one-pan dinner, ready in about an hour.
Pioneer Woman Chicken Biscuit Casserole Ingredients
- 2 (10.5 ounce) cans cream of chicken soup
- 1 cup milk
- 1 teaspoon garlic powder
- ½ teaspoon rotisserie seasoning
- ½ teaspoon black pepper
- 1 (12 ounce) can refrigerated biscuits
- 1 cup frozen peas and carrots
- 1 cup shredded cheddar cheese
- 2 cups cooked chicken (shredded or diced)
- ¼ cup sliced green onion (optional)
How To Make Pioneer Woman Chicken Biscuit Casserole
- Prep Oven and Sauce: Preheat your oven to 375°F. Spray a 9×13-inch baking dish with nonstick cooking spray. In a large bowl, whisk together the cream of chicken soup, milk, garlic powder, rotisserie seasoning, and black pepper until smooth.
- Add Biscuits and Fillings: Open the can of biscuits and cut each one into fourths. Add the biscuit pieces to the bowl with the sauce and stir to coat. Add the frozen peas and carrots, shredded cheddar cheese, and the cooked chicken. Stir until everything is well combined.
- Assemble and Bake: Pour the mixture into the prepared baking dish and spread it into an even layer.
- Bake Until Golden: Bake, uncovered, for 35-45 minutes. The casserole is done when the biscuits have puffed up and turned golden brown, and the sauce is bubbling around the edges.
- Rest and Serve: Let the casserole cool for a few minutes before serving. Top with sliced green onions, if desired.

Recipe Tips
- How do I know the biscuits are cooked through? The biscuits in the center of the casserole will take the longest to cook. If the top is getting too brown but you’re unsure if the center is done, you can cover the dish with foil and bake for a few extra minutes.
- Can I use different seasonings? Yes! This recipe is very versatile. You could swap the rotisserie seasoning for about a teaspoon of ranch seasoning or a zesty Cajun seasoning for a different flavor profile.
- What if I can only find large biscuits? If you’re using a can of larger “Grands” style biscuits, you will only need to use about 6 of them. Cut these larger biscuits into sixths instead of fourths.
- Can I add other vegetables? Absolutely. A cup of frozen corn or some sautéed mushrooms would be a delicious addition to this casserole.
What To Serve With Chicken Biscuit Casserole
This is a hearty, all-in-one meal, but it also pairs nicely with simple sides:
- A simple green salad with a light vinaigrette
- Steamed green beans or roasted broccoli
- Applesauce
How To Store Chicken Biscuit Casserole
- Refrigerate: Cover the cooled casserole tightly with foil or transfer leftovers to an airtight container. It will keep in the refrigerator for up to 3 days.
- Reheating: Reheat individual portions in the microwave or the whole casserole in a 350°F oven until warmed through. The biscuits may soften upon reheating.
- Freeze: Freezing is not recommended for this recipe, as the texture of the biscuits and the cream sauce can change upon thawing.
Pioneer Woman Chicken Biscuit Casserole Nutrition Facts
- Calories: 397kcal
- Carbohydrates: 33g
- Protein: 22g
- Fat: 20g
Nutrition information is estimated and may vary based on ingredients and cooking methods used.
FAQs
Can I make this ahead of time?
This casserole is best assembled right before baking. Preparing it too far in advance can cause the raw biscuit dough to become soggy in the sauce.
Can I use homemade biscuits?
It’s not recommended for this specific u0022bubble upu0022 style casserole. The canned refrigerated biscuits are designed to bake correctly while submerged in the sauce.
What’s the best shortcut for the chicken?
A store-bought rotisserie chicken is a fantastic time-saver! Simply shred the meat from one chicken (you’ll need about 2 cups) and you’re ready to go.
Try More Pioneer Woman Recipes:
- Pioneer Woman Chicken Alfredo Bake Recipe
- Pioneer Woman Ground Chicken Meatloaf Recipe
- Pioneer Woman Cashew Chicken Recipe
Pioneer Woman Chicken Biscuit Casserole Recipe
Description
A comforting and easy one-pan meal with tender chicken, vegetables, and cheesy biscuit pieces all baked together in a creamy sauce.
Ingredients
Instructions
- Preheat oven to 375°F. Spray a 9×13-inch baking dish.
- In a large bowl, whisk together the soup, milk, and seasonings.
- Cut each biscuit into fourths and stir them into the soup mixture.
- Add the peas and carrots, cheddar cheese, and chicken. Stir to combine.
- Pour into the prepared baking dish.
- Bake for 35-45 minutes until the biscuits are golden brown and the sauce is bubbly.
- Let rest for a few minutes before serving.
Notes
- u003cliu003eUsing a rotisserie chicken is a great shortcut that saves time and adds flavor.u003c/liu003eu003cliu003eIf the top of the casserole is browning too quickly, you can cover it with foil for the remainder of the baking time.u003c/liu003eu003cliu003eThis is a very forgiving recipe; feel free to swap the cheddar for another favorite cheese like Colby Jack.u003c/liu003eu003cliu003eThe biscuit pieces will puff up and u0022bubble upu0022 through the sauce as they bake.u003c/liu003e
